The first episode is entitled One Love. Jackie is the campus queen, rich, beautiful and liked by everyone except Che, who thinks that Jackie is just a shallow brat. After being forced to work together for school activities, Jackie made it a personal goal for Che to like her. Two Hearts is the second episode. Enzo is a star soccer player at school who loves the attention that he gets. However, he takes many things for granted, this changes when he gets a heart problem and doctors say that only a transplant can save his life.

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Bea Alonzo

Bianca (segment "Two Hearts")

John Lloyd Cruz

Enzo (segment "Two Hearts")

Heart Evangelista

Jackie (segment "One Love")

John Prats

Che (segment "One Love")

Cherie Gil

Jackie's Mom (segment "One Love")

Susan Africa

Che's Mom (segment "One Love")

Madeleine Humphries

Guia (segment "One Love")

Pauleen Luna

Shanni (segment "One Love")

Anna Larrucea

Rhoda (segment "Two Hearts")

Joel Torre

Dante (segment "Two Hearts")

Kathleen Hermosa

Janice (segment "Two Hearts")

Drew Arellano

Ryan Gatmaitan (segment "One Love")

Dominic Ochoa

Jojo (segment "Two Hearts")

Liza Lorena

Lola (segment "Two Hearts")

Chanda Romero

Josie (segment "Two Hearts")

John Lapus

Tiger (segment "One Love")

Joshua Dionisio

Xavier (segment "Two Hearts")

Bonggoy Manahan

Jackie's Dad (segment "One Love")

Edwin Reyes

Che's Dad (segment "One Love")

Edwin Reyes

Yaya Glow (segment "One Love")

Sarita Perez de Tagle

Celine (segment "One Love")

Dianne Tejada

Pia (segment "One Love")

Maoui David

Ria (segment "One Love")

Nicholas Garcia

Edgar (segment "One Love")

Chat Silayan

Azon (segment "Two Hearts")

Mico Palanca

Kiko (segment "Two Hearts")

Allyzon Lualhati

Carla (segment "Two Hearts")

Vivian Foz

Nelly (segment "Two Hearts")

Mandy Ochoa

Edgar (segment "Two Hearts")

Artemio Abad

Doctor (segment "Two Hearts")

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