Noel

Susan Sarandon

Rose Collins

Paul Walker

Mike Riley

Penélope Cruz

Nina Vasquez

Alan Arkin

Artie

Marcus Thomas

Jules Calvert

Sonny Marinelli

Dennis

Daniel Sunjata

Marco

Chazz Palminteri

Arizona

Robin Williams

Charlie Boyd / The Priest

Rob Daly

Paul

John Doman

Dr. Baron

Billy Porter

Randy

Carmen Ejogo

Dr. Batiste

Donna Hanover

Debbie Carmichael

Merwin Mondesir

Glenn

Una Kay

Helen

Sonia Benezra

Aunt Sonya

Marcia Bennett

Nurse Stein

Howard Rosenstein

ER Doctor

Jane Wheeler

Karen

David Julian Hirsh

Barton

Marguerite Kinh

Mrs. Lee

Arthur Holden

Piano Player

Maurizio Terrazzano

Tom

Rachelle Lefevre

Holly

Erika Rosenbaum

Merry

Charles Rosenblum

Coffee Vendor

Victoria Sanchez

Young Mother

Scott Faulconbridge

Man in Front Row

Budd Mishkin

NY1 Reporter

Carmen Echeverria

Young Girl

Gianpaolo Venuta

Young Guy

Nicholas Haze

Waiter

Ruth Chiang

Nurse Woo

Kevin Ryder

Bartender

Andy Bradshaw

Security Guard #1

Robert Newton Brown

Security Guard #2

Bill Corday

Meek Man

Jennifer Seguin

Young Woman

Lindsay Owen Pierre

Friend

David Schaap

Man with Head Injury

Lynne Adams

Head ER Nurse

Kathleen Mackey

Heather

Donna Giaimo

Singing Nun of the Daughters of St. Paul

Fay Josephine Pele

Singing Nun of the Daughters of St. Paul

Bridget Charles Ellis

Singing Nun of the Daughters of St. Paul

Mary R.G. Grissom

Singing Nun of the Daughters of St. Paul

Kathryn J. Hermes

Singing Nun of the Daughters of St. Paul

Bernadette M. Reis

Singing Nun of the Daughters of St. Paul

Margaret Timothy Sato

Singing Nun of the Daughters of St. Paul

Patricia C. Shaules

Singing Nun of the Daughters of St. Paul

Patricia C. Shaules

Singing Nun of the Daughters of St. Paul

Nancy M. Usselmann

Singing Nun of the Daughters of St. Paul

Christina M. Wegendt

Singing Nun of the Daughters of St. Paul

Gabriella Palminteri

Girl in Red Coat

James Callaghan

Extra (uncredited)

Isabelle Champeau

Party Guest (uncredited)

Lucinda Davis

Nurse Gomez (uncredited)

Francesco Giannini

Family member (uncredited)

Chantal Lonergan

Joy (uncredited)

Dante Palminteri

Boy in Hospital (uncredited)

Adrianne Richards

Nurse Kline (uncredited)

Derek Schnobb

Boy (uncredited)